PE-22-28 10mg
Researched Benefits:
- Selective TREK-1 potassium channel antagonist for investigating antidepressant-like signaling pathways
- Facilitates analysis of hippocampal brain-derived neurotrophic factor expression and activation
- Supports research on glutamatergic neurotransmission modulation and synaptic plasticity in assays
- Enables evaluation of rapid-acting neurogenic responses within controlled cellular assay models
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Description
Description
PE-22-28 10mg is a potent, short-chain research peptide (7 amino acids) derived from the spadin sequence and recognized for its high-affinity inhibition of the TREK-1 potassium channel. Manufactured from premium raw materials with state-of-the-art synthesis techniques, our PE-22-28 offers exceptional purity and stability, supporting rigorous neurological and psychiatric research applications.
Key Features:
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≥95 % purity verified through rigorous HPLC analysis
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Consistent batch-to-batch quality under cGMP-aligned production standards
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Supplied lyophilized to ensure long-term stability when stored at −20 °C
Applications:
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Investigating rapid-onset antidepressant mechanisms and mood stabilization
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Exploring hippocampal neurogenesis and synaptic plasticity pathways
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Studying neuroprotection and recovery following ischemic stroke or traumatic brain injury
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Evaluating TREK-1 channel modulation in neurodegenerative disease models
Specifications and Documentation
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Material Safety Data Sheet (MSDS):Â Coming Soon.
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Handling and Storage Instructions:Â Coming Soon.
PE-22-28 10 mg stands out in pre-clinical neuroscience for its capacity to induce rapid neurochemical and behavioral adaptations, making it an invaluable tool for researchers probing novel therapeutic avenues in mental health and neuroprotection.
Additional information
| CAS No. | 1801959-12-5 |
|---|---|
| Purity | ≥99% |
| Sequence | GVSWGLR |
| Molecular Formula | C35H55N11O9 |
| Molecular Weight | 773.89 g/mol |
| Applications | Depression models, neurogenesis studies, stroke recovery, TREK-1 inhibition |
| Synthesis | Solid-phase synthesis |
| Solubility | Soluble in water or 1% acetic acid |
| Stability & Storage | Stable for up to 24 months at -20°C. After reconstitution, may be stored at 4°C for up to 4 weeks or at -20°C for up to 6 months. |
| Appearance | White lyophilized powder |
| Shipping Conditions | Shipped at ambient temperature; once received, store at -20°C |
| Regulatory/Compliance | Manufactured in a facility that adheres to cGMP guidelines |
| Safety Information | Refer to provided MSDS |
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